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you wouldn't think things like diaper

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rash or thrush could be studied on the

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International Space Station but an

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investigation is looking at that type of

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bacteria come into us here on earth to

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see how it reacts in microgravity we

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work with the yeast it's called Candida

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albicans that causes fairly common and

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superficial diseases and infections such

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as thrush fungal nails diaper rash and

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it can also cause more serious systemic

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sort of potentially fatal diseases as

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well and you've completed your

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experiment correct our experiment went

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up in October of 2012 and spent about 28

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days on ISS so why is the ISS an ideal

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place to study things that may cause

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diaper rash or something like that right

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well like I said Canada is a fairly

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common yeast about twenty-five percent

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of the population is exposed to it at

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some point and if you combine that with

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the reality that we've heard here and

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we've heard lots of places that

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astronauts have a somewhat compromised

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immune system and then if you combine

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that with a potentially infectious agent

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that's why NASA is interested in it and

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that's why it's really important to be

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able to study in an environment where

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there is prolonged exposure to those

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microgravity sort of extreme environment

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conditions how would that bacteria get

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to the space station so this is a yeast

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that can be that we can be carriers of

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it and so we can carry it along with us

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when when we're moving around and as an

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opportunistic pathogen a lot of times it

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doesn't cause disease we don't even

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really know it's there and it's only

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when we have somewhat of a compromised

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immune system that it gets to do its

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thing so how did the experiment work

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exactly on station so basically

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everything is self-contained the way we

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did it and we grew cells in liquid

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culture the the differences is just the

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technology and the hardware portion of

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it so we use what we call tricked-out

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test tubes if you will where the in the

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within the test tube the cells are

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separate from their media and separate

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from the sort of fixative agent at the

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very end

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and the crew member just basically

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activates them by turning a crank at

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given times to initiate cell growth and

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then ultimately to halt cell growth so

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we get we got cells back sort of in

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these contain tubes some of them had

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already been fixed on station we also

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got some cells back viable which was an

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important part of the experiment we

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weren't sure with all the time

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constraints whether it's cells would

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actually come back viable and in a

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position that we could test them once

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they got back to the lab and in fact

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that worked well so what have we learned

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have you learned anything so far oh

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we've learned a lot it was our first

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exposure to International Space Station

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type of research and we flew on space

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expedition crs-1 so the learning curve

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was steep but scientifically you know

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some other things that we predicted were

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going to happen did we found that the

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yeast was a little bit more resistant to

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antifungal agents we also found that it

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was a little it it could overcome the

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monocytes a little bit when we tested

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that we also found some things that

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didn't change as we predicted the cell

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shape the colony basically when it when

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it grows as a colony that structure both

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of those structures really weren't as we

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predicted but that's why we do the

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experiments and that will do it for us

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here from the payload operations

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integration Center in Huntsville now